Moreover, the observation of increased KA1 expression in both adrenalectomy and CRS, however, is similar to what has been observed for the glutamate transporter, GLT-1, namely, an increased expression of GLT-1 after CRS but also an increase after ADX that is reversed by adrenal steroid replacement [35], [36]. The gene discussed is GRIK4; the disease is congenital rubella syndrome.