The assembly of RAD51 at DNA damage sites is regulated by a number of RAD51 cofactors, including the tumor-suppressor gene BRCA1 (Breast Cancer Susceptibility Gene 1), BRCA2, and five RAD51 paralogs (RAD51B/C/D and XRCC2/3) (reviewed in [11],[12]). This evidence concerns the gene RAD51 and breast cancer.