GNRH1 and uterine corpus leiomyoma: Although non-surgical treatment using gonadotropin-releasing hormone (GnRH) agonist is effective for reducing the size and symptoms of uterine fibroids, surgical treatment is also needed for patients with potential indications such as abnormal uterine bleeding unresponsive to hormone, urinary symptoms or signs such as hydronephrosis and infertility with uterine fibroids as the only abnormal finding.