Thus, the ability of albumin dialysis to remove other toxins and pro-inflammatory stimuli such as lipopolysaccharides and lipid peroxidation end-products may have implications for limiting the inflammatory response that could be implicated not only in renal impairment and circulatory dysfunction but also in the pathophysiology of hepatic encephalopathy in patients with severe liver failure [37]. This evidence concerns the gene ALB and Hepatic failure.