EBAG9 and cancer: RCAS1 expression has also reportedly been associated with the markers of poor prognosis in various types of cancers, such as the presence of lymph node metastases in gallbladder cancer [12] and the high grade of tumor cells in ductal breast and lung cancers [19,10]; it has additionally been associated with the presence of tumor invasion in vessels and nerves, and with the depth of tumor invasion in gallbladder cancer [12].