As RCAS1 expression has not been analyzed in pharyngeal and laryngeal squamous cell carcinomas and their healthy stroma, yet has been shown to be involved in tumor invasion, we decided that the levels of RCAS1 expression should be analyzed with respect to the clinicopathological features and that patients who underwent surgery due to pharyngeal and laryngeal squamous cell carcinomas should be followed up for 4 years. Here, EBAG9 is linked to laryngeal squamous cell carcinoma.