111In-(DTPA)-D-Phe1-octreotide binds to somatostatin receptors, predominantly of somatostatin receptor subtype sst2 and sst5, and have been useful for diagnostic nuclear medicine imaging of neuroendocrine tumors and of non-neuroendocrine tumors which express somatostatin receptors [26,108]. This evidence concerns the gene SSTR5 and neuroendocrine neoplasm.