For some of the TFs not previously reported to be deregulated in CRC, the involvement in the tumorigenesis of other cancers has been well established for example, SOX4 in bladder cancer and CBFB in acute myeloid leukaemia (Kundu et al, 2002; Aaboe et al, 2006). This evidence concerns the gene SOX4 and urinary bladder carcinoma.