ERBB2 and gastric carcinoma: Earlier studies in gastric carcinomas reported ERBB2 overexpression using immunohistochemistry (IHC) in 5.2–22.6% of the cases, whereas the proportion with ERBB2 amplification evaluated using fluorescence in situ hybridisation (FISH) ranged from 3.8 to 12.2% (Takehana et al, 2002; Varis et al, 2004; Park et al, 2006; Kim et al, 2007).