DLEC1 and nasopharyngeal carcinoma: Considering promoter CGI and the chromosome location of identified genes, among the 22 targets identified, one regarded to be of particular interest is DLEC1 (Daigo et al, 1999), which is located at the commonly deleted locus 3p22.3 and recently reported to be methylated in lung, ovarian and nasopharyngeal carcinomas (Kwong et al, 2006, 2007).