MYOM2 and neoplasm: Some or all of the following criteria would constitute evidence for the diagnosis of myeloma: evidence of M-protein in the serum or urine (usually ≥ 30 g/L); at least 10% plasma cells on a myelogram; demonstration of monoclonal plasma cells on bone marrow biopsy; and end-organ damage that may be hypercalcaemia, renal insufficiency, anemia, osteolytic bone lesions or extramedullary dissemination of myeloma tumour cells [3,5].