Of the 273 HEV71 culture positive children, 187 (69%) had mild HFMD, 34 (13%) had HFMD-Non-CNS, and 52 (19%) had HFMD-CNS (30 had ASM, 19 had encephalitis, 1 had AFP and 2 had encephalitis with cardiorespiratory failure). Here, AFP is linked to encephalitis.