An example of the latter is the karyotypically cryptic translocation t(12;15)(p13;q25), resulting in the ETV6:NTRK3 fusion gene, which occurs in histologically and developmentally completely disparate tumors such as kidney and breast tumors, infantile fibrosarcoma, and acute myeloid leukemia [22]. The gene discussed is ETV6; the disease is acute myeloid leukemia.