ITGAE and infection: Since the MHC IIhi CD103+ and CD11bhi RDC as well as the MoRDC were present in both the normal and infected lungs, the accumulation of DC with the same phenotypes in the MLN draining infected lungs most likely reflected the accelerated migration of these DC subsets from the lungs to the draining nodes in response to infection rather than recruitment of DC progenitors from the bone marrow to the MLN or the de novo differentiation/maturation of CD103−CD11blo/med LN-resident DC into these respective DC subsets upon infection.