To better define the role of these migrant RDC subsets as well as the other DC subsets found in the MLN after infection in the antigen presentation to naïve T cells, we first isolated (after mechanical lymph node disruption) the major CD11c+ DC populations (i.e., primarily of CD103+ DC, CD11bhi DC, Gr-1+ MoDC and a smaller number of B220+ pDC) from the MLN of influenza-infected mice at d3 p.i. (Fig. S9). This evidence concerns the gene ITGAX and influenza.