Putative translocation partners of EWSR1 are therefore genes assigned to the breakpoints of these amplifications:RPN2, BLCAP, CDH22, SLC13A3, EYA2, NCOA3, Kua-UEV, and NFATC2. Based on literature, the most interesting candidates are EYA2 (located at 20q13.12), which has been found to function as a transcriptional activator in ovarian cancer cells [29], and NFATC2 (located at 20q13.2), which functions in positive regulation of transcription [30]. The gene discussed is EWSR1; the disease is ovarian carcinoma.