According to our integrated analysis of array CGH and expression data including 16 ESFT patient samples, we selected as one of the most interesting putative target genes within the common 1q22-qter gain gene HDGF, which has been reported as a putative prognostic marker for several tumor types, e.g., gastrointestinal stromal tumors (GIST) [31,32], hepatocellular carcinoma [33], non-small-cell lung carcinoma [34,35] and pancreatic ductal carcinoma [36]. This evidence concerns the gene HDGF and gastrointestinal stromal tumor.