TLR2 and neoplasm: Intratumoral delivery of WT DC pulsed with GL26 tumor extract mediated regression of intracranial brain tumors in WT mice (*, p < 0.05 versus saline; MSR 1.2; Figure 5B), whereas TLR2−/−-derived DC pulsed with GL26 tumor extract failed to induce brain tumor regression (Figure 5B).