Portal vein thrombosis, metastases, lymph node involvement, gross HCC*, tumour size, tumour number, tumour histology, tumour stage, tumour echo†, tumour margin‡, tumour doubling time, encapsulation§, SUV ratio, AFP, AFP-L3, DCP, LAK, NK, p53, IL-8, LINE-1, CRP, TGF-β, HGF, Milan criteria¶. The gene discussed is AFP; the disease is neoplasm.