When the 22 studies in which 100% of the patients had cirrhosis are analysed (11, 12, 14, 19, 23, 24, 26, 27, 32, 35, 36, 38, 47, 52, 53, 60, 62, 68, 69, 71, 78, 79) (Table 7), the most common predictors of death found in over three studies are the CLIP score, tumours that were untreated, tumour size, the Child–Pugh class, tumour number, AFP and portal vein thrombosis. The gene discussed is AFP; the disease is neoplasm.