RT-PCR analysis of normal lung tissue from A/J and C57BL/6J mice, which carry different alleles of this gene, and of normal lung and tumor tissue from (A/J×C57BL/6J)F1 mice revealed no Lasc1-specific transcript fragments in either normal or tumor lung tissue, whereas genomic DNA was clearly amplified (Figure 4, top) and the Itpr2 or Gapdh positive controls were readily detected in cDNA samples (Figure 4, bottom and data not shown). Here, GAPDH is linked to neoplasm.