Of these, IFN-γ, produced by activated T cells and NK cells, in conjunction with other cytokines such as IL-12, is thought to enhance the cytolytic activity of NK cells to attach and kill tumor cells [17–19], indicating that oral administration of JTT into mice increases the levels of cytokines, including IFN-γ and IL-12 in the lung tissues and results in prevention of tumor cell colony formation. This evidence concerns the gene IFNG and neoplasm.