Although mutation of the Gadd45 gene is not common in tumors [13,14], some research has been reported showing that point mutations of Gadd45 gene at exon 4 were found in 13.6% of pancreatic cancer cases, suggesting the possibility that Gadd45 is dysfunctional in this tumor type [15]. The gene discussed is GADD45A; the disease is pancreatic neoplasm.