MUC4 and carcinoma: In the four series, survival in MUC4-positive or high-expression cases was significantly worse than that for MUC4-negative or low-expression cases, and multivariate analyses showed that MUC4 expression in the carcinomas was a risk factor for a poor prognosis (Shibahara et al, 2004; Saitou et al, 2005; Tamada et al, 2006; Tsutsumida et al, 2007).