BIRC5 and breast cancer: As shown in Fig. 4A, CTLs induced from PBMCs of a breast cancer patient were capable of killing survivin-C58-pulsed T2-A24 target cells, but they failed in killing SYT-SSX-derived peptide-pulsed T2-A24 cells or survivin-C58-pulsed HLA-A24-negative target cells.