Meanwhile, genetic factors also play an important role in VKH syndrome as evidenced by the increased rates of this syndrome in pigmented groups [2], familial aggregation [5-7], and strong association with human leukocyte antigens (HLA)-DR4 and HLA-DRw53 in various ethnic groups including the Chinese and Japanese [8-10]. The gene discussed is TNFRSF10A; the disease is Vogt-Koyanagi-Harada disease.