STAT4 and systemic lupus erythematosus: These include PTPN22, associated with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), T1D, and Graves' Disease (GD) [2], STAT4, associated with SLE and RA [3], and the IL7R and KIAA0350 gene regions, which are shared between T1D and MS [4]–[6].