Our results were consistent with those of the meta-analysis such that GSN, SPTBN1, SFRP1 and MAF were down-regulated in most tumor samples with respect to their matched non-tumor samples whereas COX6C, RAD21, GSPT1, NME1 and PTTG1 were up-regulated (Figure 5). The gene discussed is NME1; the disease is neoplasm.