For example, ADAMTS1, ATF3, IGFBP6, PRNP, EGFR, FN1, ID4, SPTBN1, and SFRP1 genes from the DN list were found to significantly different in expression between nonbasal-like vs. basal-like tumors as well as basal and luminal subtypes of the breast tumors (p < 0.05). This evidence concerns the gene IGFBP6 and breast neoplasm.