CDC6 and intraepithelial neoplasia: However, a statistically significant difference in CDC6 expression was not observed between the mild and moderate epithelial dysplasia (p = 0.912), between moderate and severe epithelial dysplasia (P = 0.451), between moderate epithelial dysplasia and SCC (p = 0.311), or between severe epithelial dysplasia and SCC (p = 0.728).