Age of onset of asthma was similar among the H. pylori+/CagA− individuals (N = 64, median age = 19, IQR = 6–30) and the CagA+ individuals (N = 71, median age = 21, IQR = 8–34), but was substantially lower among the H. pylori negative individuals (N = 159, median age = 11 y, IQR = 5–23) (p = 0.006). Here, S100A8 is linked to asthma.