Vaccination with self-HSP60 or its peptide epitopes can arrest the development of type 1 diabetes (T1DM), spontaneous or induced, in non-obese diabetic (NOD) mice [1], [2], [3] and in other mouse models [4]; HSP60 vaccination can also inhibit adjuvant arthritis (AA) in rats [5], [6], [7]. The gene discussed is HSPD1; the disease is type 1 diabetes mellitus.