Univariate analyses revealed that a tumor size of 2 cm or more (HR = 6.7, p < 0.0001), nodal positivity (HR = 4.79, p < 0.0001), nuclear grade 3 (HR = 3.96, p < 0.0001), a high HER2 level (HR = 2.11, p = 0.031), positive Ki67 (HR = 2.25, p = 0.0016), positive p53 (HR = 2.35, p = 0.0024), and positive CENP-F (HR = 3.92,p < 0.0001) revealed higher recurrence rates. The gene discussed is CENPF; the disease is neoplasm.