However, the human LMO4 gene is located on chromosome 1p22.3 [35], which is a region deleted in several human cancers, such as those of liver, skin, and lung [36,37], and Setogawa et al reported that the tumor suppressor LKB1 induces p21 expression in collaboration with LMO4, suggesting that LMO4 may have a tumor suppressor function [34]. Here, STK11 is linked to cancer.