To evaluate whether CE hasany influence on glucose tolerance, IPGTT determination was carried outfor overnight fasted DIO mice at 0 minute, 15 minutes, 30 minutes, 60 minutes,and 120 minutes following 2 g/kg glucose intraperitoneal injection DIOmice developed severe insulin resistance after 5 months high-fat food inductions,and serum insulin level increased nearly 3 times compared to the control miceon normal diet (see Table 1). This evidence concerns the gene INS and Insulin resistance.