DSG2 and pancreatic adenocarcinoma: An examination of Dsg2 immunoreactivity revealed that the most intense staining (3+) was observed in the normal pancreatic tissues (28.4%), although the chronic pancreatitis samples (11.2%) still showed a higher average percentage of cells with 3+ intensity compared to the pancreatic adenocarcinoma samples (4.3%) (Fig. 2D).