Recently, TLR2-deficient mice showed elevated levels of murine CMV (MCMV) in the spleen and liver 4 days post-infection as compared to wild type (wt) C57BL/6 mice and this difference in viral titers was abrogated by in vivo depletion of NK cells of TLR2-deficient mice and C57BL/6 mice using anti-NK1.1 antibodies [43]. This evidence concerns the gene TLR2 and infection.