EGFR expression has been demonstrated in 43–67% of patients with endometrial cancer and its association with clinical outcome has been explored with some studies demonstrating an association between EGFR expression and poor clinical outcome (Khalifa et al, 1994; Scambia et al, 1994; Niikura et al, 1995) whereas others show no association (Reinartz et al, 1994). The gene discussed is EGFR; the disease is endometrial cancer.