CXCL9/Mig, CXCL10/IP-10 and CXCL11/ITAC, ligands for CXCR3, and CCL5/RANTES, ligand for CCR5, were shown to be elevated in sputum from COPD patients compared with nonsmokers [12]. Here, CCL5 is linked to chronic obstructive pulmonary disease.