Recent reports demonstrated that CCR6, together with its ligand CXCL20/MIP-3α, was involved in CS-induced lung inflammation and that the interaction between CCR6 and CCL20/MIP-3α could also mediate accumulation of dendritic cells (DCs) in the lungs of COPD patients [16,17]. The gene discussed is CCL20; the disease is chronic obstructive pulmonary disease.