CDKN2A and cervical squamous intraepithelial neoplasia: Antibodies that are directed against p16-INK4A allow selective staining of high-risk HPV-infected histological sections or of cytological smears, but not other cervical epithelia, suggesting that detection of this marker could provide diagnostic support to distinguish true CIN/dysplasia from immature metaplasia or other non-neoplastic changes of the cervix [128-131] and to improve interpretation of histology [132].