THBS1 and neoplasm: In these studies, ABT-510 induced apoptosis in tumor cells and diminished angiogenesis and proliferation.(70) In the ApcMin+/model, ABT-510 administration using osmotic mini-pumps significantly diminished the number of adenomas compared with mice controls.(71) Angiocidin a peptide with TSP1 binding activity has been effective in a human colorectal xenograft model.