There were no significant differences between cardioembolic stroke and non-cardioembolic stroke in these parameters, with the exceptions of plasma BNP and distribution of Af and mitral regurgitation: plasma BNP was significantly increased in the cardioembolic stroke patients compared with the non-cardioembolic stroke patients, and Af was highly distributed in cardioembolic stroke (p < 0.001; respectively). This evidence concerns the gene NPPB and cardioembolic stroke.