Furthermore, we found an increased number of BrdU/NeuN double-labeled cells in the SVZ and affected striatum of TGF-β1 treated group at the anaphase after stroke, whereas only a few cells were GFAP positive, which suggest that intranasal administration of TGF-β1 also promoted progenitor's differentiation towards a neuronal lineage. The gene discussed is RBFOX3; the disease is Stroke.