Similarly, the Naderi cohort also showed positive associations between high BAG-1 expression and ER+ (P=0.0014), HER-2 negativity (P=0.0044) and low histological grade (P=0.0061) but not with tumour size or lymph node status (P=0.081 and P=0.106, respectively). This evidence concerns the gene ERBB2 and neoplasm.