Expression of the αv and β3 integrin subunits and of osteopontin was stronger in melanomas than in benign nevi (p = 0.034, p = 0.001 and p < 0.0001, respectively), whereas the expression of CD44 was weaker in melanomas than in nevi (p = 0.038) (Table 2). This evidence concerns the gene SPP1 and melanoma.