ALB and Alzheimer disease: When sCJD patients were compared to control groups A, C, and AD patients, the sensitivity and specificity of elevated urinary α1-ACT for sCJD were, respectively, 72.4%, 87.5% (μg/mg albumin) or 89.7%, 100% (μg/g creatinine) if Control group C is not included in the calculation, and 79.3%, 94.7% (μg/mg albumin) or 96.6%, 100% (μg/g creatinine) if Control group C is included in the calculation (Fig 5).