CD79A and nasopharyngeal carcinoma: Therefore, the exclusive high percentage of LE tumors in NPC patients together with the unusual high levels of EBV serum IgG and IgA in NPC versus other HNCA groups and in LE group versus SCC group of NPC patients have led to the suggestion that EBV in the Middle East, or might be in any other high endemic region, plays a central role in the NPC development favoring LE histology on other types of HNCA histology.