The first results for 2003 showed average BC care as provided by the initial group of 59 participating centres to be reasonably satisfactory, e.g. with regard to axillary dissection (QI No. 2), complete tumour staging data (QI No. ex-3) and hormone receptor assessment (QI No. 5), but in need of improvement in other respects, e.g. endocrine therapy in hormone receptor-positive patients, radiotherapy after breast-conserving therapy and radiotherapy after mastectomy (QIs Nos. The gene discussed is NR4A1; the disease is breast cancer.