EGFR and non-small cell lung carcinoma: The presence of EGFR mutations has been proposed to be a positive prognostic factor (Eberhard et al, 2005), whereas high-EGFR copy number and the presence of KRAS mutations have both been associated to poor prognosis in resected NSCLC patients (Nelson et al, 1999; Hirsch et al, 2003; Massarelli et al, 2007).