In panel B, the densitometry results (mean ± SEM) are expressed as the fold difference compared to baseline, the phosphorylation of MLC20 was increased at 1 minute after treatment with IL-8 consistent with activation of contractile signaling pathways and was significantly greater in CF cells (1.5 fold) than in control cells (1.2 fold). Here, CXCL8 is linked to cystic fibrosis.