Indeed, although the role ofPPARγ will be discussed in thisreview, since there is considerable information on PPARγ in cancer [35] and an article on PPARγ regulation of the angiogenicswitch in this review series [36], this manuscript willfocus more on recent observations highlighting novel roles for PPARα and PPARβ/δ in endothelialcell function and in particular on the regulation of angiogenesis. Here, PPARG is linked to cancer.