IL1B and keratoconus: In the screen of four SNPs of IL1B, the genotypes of –511 *C/*C and –31 *T/*T of IL1B SNPs were associated with a 1.96 fold and 1.92 fold greater risk of developing keratoconus, respectively, (p=0.025 and p=0.027, respectively), showing a strong statistical association with keratoconus in unrelated patients.