TGFB1 and metabolic dysfunction-associated steatohepatitis: An animal model of "fibrosing steatohepatitis" that replicates the histologic features of human NASH stresses the sequence of steatosis, inflammatory cell injury and fibrogenesis, mediated by hepatic stellate cells (HSCs) via up-regulation of transforming growth factor-beta1 (TGF-β1) [3].