As shown in Table 2, lymph node metastasis was correlated with cytoplasmic CXCR4 expression (p = 0.0144), VEGF-C expression (p = 0.0123), and recombination of cytoplasmic CXCR4 and VEGF-C expression (p = 0.0081). This evidence concerns the gene CXCR4 and metastatic malignant neoplasm in the lymph nodes.