The R7041 infection significantly increased the intracellular expression of MxA when compared to its rescue virus R7306 (5 moi, P < 0.001), HSV-1 (F)-infected (1 moi, P = 0.003 and 5 moi, P = 0.033) or uninfected (5 moi, P = 0.040) cells at 24 h p.i. (Figure 4C). This evidence concerns the gene MX1 and infection.